Switching hunger off

For years massive research funds have been flowing into weight-loss or diet pills.
But recently scientists tried a different approach: the brain.

In mice scientists found a circuit that involved specifick neuron cells inside the brain. With the right chemical they could ' block' or 'unblock' the signal and essentially make the mice experience hunger or loose their apetite.

It needs to be determined if humans have a smilar circuit and if other forms of switches exist. Turn off pain, feeling or increasing certain sensations.

more reading can be done here:

• A neural basis for melanocortin-4 receptor–regulated appetite (original article)

• Brain's Hunger 'Switch' May Regulate Appetite
  Targeting MC4R brain circuit stimulated hunger, satiety in genetically-altered mice.

• Brain’s 'hunger hub' could be switched off